L10F (p.Leu10Phe) variant of HLA-B (P01889)
L10F (p.Leu10Phe) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
L10F (p.Leu10Phe) variant details
- p.Leu10Phe
- 1000Genomes rs749523872
- ExAC rs749523872
- gnomAD rs749523872
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.12
- CADD 20.60
- PolyPhen-2 0.02
- SIFT 0.07
- Most common in the Ashkenazi Jewish population (allele frequency 0.00012)
- Structural context available