H27Q (p.His27Gln) variant of HLA-B (P01889)
H27Q (p.His27Gln) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
H27Q (p.His27Gln) variant details
- p.His27Gln
- Ensembl rs137854636
- Missense
- Variant Prioritization Score for Impact Estimate 0.324
- REVEL 0.20
- CADD 22.90
- PolyPhen-2 0.04
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.8e-06)
- Structural context available