G40S (p.Gly40Ser) variant of HLA-B (P01889)
G40S (p.Gly40Ser) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
G40S (p.Gly40Ser) variant details
- p.Gly40Ser
- cosmic curated COSV10593
- gnomAD rs1399078190
- Missense
- Variant Prioritization Score for Impact Estimate 0.297
- REVEL 0.12
- CADD 24.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 0.00014)
- Structural context available