F46L (p.Phe46Leu) variant of HLA-B (P01889)
F46L (p.Phe46Leu) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
F46L (p.Phe46Leu) variant details
- p.Phe46Leu
- Ensembl rs137854656
- Missense
- Variant Prioritization Score for Impact Estimate 0.309
- REVEL 0.22
- CADD 15.50
- PolyPhen-2 0.04
- SIFT 0.02
- Most common in the East Asian population (allele frequency 3.7e-05)
- Structural context available