F46C (p.Phe46Cys) variant of HLA-B (P01889)
F46C (p.Phe46Cys) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
F46C (p.Phe46Cys) variant details
- p.Phe46Cys
- gnomAD rs1767127680
- Missense
- Variant Prioritization Score for Impact Estimate 0.315
- REVEL 0.28
- CADD 11.10
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 3e-05)
- Structural context available