E43* (p.Glu43Ter) variant of HLA-B (P01889)
E43* (p.Glu43Ter) in HLA-B (P01889) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
E43* (p.Glu43Ter) variant details
- p.Glu43Ter
- rs137854653
- NCI-TCGA Cosmic COSV6952
- cosmic curated COSV69521
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.612
- CADD 35.00
- UniProt: Variant assessed as somatic; high impact.
- Population evidence available
- Structural context available