E21D (p.Glu21Asp) variant of HLA-B (P01889)
E21D (p.Glu21Asp) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
E21D (p.Glu21Asp) variant details
- p.Glu21Asp
- gnomAD rs1326884077
- Missense
- Variant Prioritization Score for Impact Estimate 0.334
- REVEL 0.16
- CADD 23.70
- PolyPhen-2 0.99
- SIFT 0.05
- Most common in the South Asian population (allele frequency 2.6e-05)
- Structural context available