D53Y (p.Asp53Tyr) variant of HLA-B (P01889)
D53Y (p.Asp53Tyr) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
D53Y (p.Asp53Tyr) variant details
- p.Asp53Tyr
- Ensembl rs281864592
- Missense
- Variant Prioritization Score for Impact Estimate 0.439
- REVEL 0.35
- CADD 28.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 3.3e-05)
- Structural context available