A18T (p.Ala18Thr) variant of HLA-B (P01889)
A18T (p.Ala18Thr) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
A18T (p.Ala18Thr) variant details
- p.Ala18Thr
- ExAC rs775725340
- gnomAD rs775725340
- Missense
- Variant Prioritization Score for Impact Estimate 0.289
- REVEL 0.15
- CADD 14.70
- PolyPhen-2 0.01
- SIFT 0.23
- Most common in the Non-Finnish European population (allele frequency 1.5e-06)
- Structural context available