A18S (p.Ala18Ser) variant of HLA-B (P01889)
A18S (p.Ala18Ser) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
A18S (p.Ala18Ser) variant details
- p.Ala18Ser
- ExAC rs775725340
- gnomAD rs775725340
- Missense
- Variant Prioritization Score for Impact Estimate 0.305
- REVEL 0.16
- CADD 18.50
- PolyPhen-2 0.22
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.5e-06)
- Structural context available