W23L (p.Trp23Leu) variant of HLA-A (P04439)
W23L (p.Trp23Leu) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
W23L (p.Trp23Leu) variant details
- p.Trp23Leu
- gnomAD 6-29942621-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.283
- REVEL 0.06
- CADD 22.50
- PolyPhen-2 0.99
- SIFT 0.11
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.8e-05)
- Structural context available
- Literature evidence available