V3A (p.Val3Ala) variant of HLA-A (P04439)
V3A (p.Val3Ala) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
V3A (p.Val3Ala) variant details
- p.Val3Ala
- gnomAD 6-29942561-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.12
- CADD 12.00
- PolyPhen-2 0.08
- SIFT 0.08
- Most common in the Latino/Admixed American population (allele frequency 4.2e-05)
- Structural context available
- Literature evidence available