T8S (p.Thr8Ser) variant of HLA-A (P04439)
T8S (p.Thr8Ser) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
T8S (p.Thr8Ser) variant details
- p.Thr8Ser
- gnomAD 6-29942575-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.17
- CADD 21.00
- PolyPhen-2 0.99
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available