T8I (p.Thr8Ile) variant of HLA-A (P04439)
T8I (p.Thr8Ile) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
T8I (p.Thr8Ile) variant details
- p.Thr8Ile
- gnomAD rs1195498708
- Missense
- Variant Prioritization Score for Impact Estimate 0.28
- REVEL 0.09
- CADD 16.70
- PolyPhen-2 1.00
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 4.9e-06)
- Structural context available