T22P (p.Thr22Pro) variant of HLA-A (P04439)
T22P (p.Thr22Pro) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
T22P (p.Thr22Pro) variant details
- p.Thr22Pro
- gnomAD rs1341761581
- Missense
- Variant Prioritization Score for Impact Estimate 0.327
- REVEL 0.18
- CADD 23.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 0.0001)
- Structural context available