T22N (p.Thr22Asn) variant of HLA-A (P04439)
T22N (p.Thr22Asn) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
T22N (p.Thr22Asn) variant details
- p.Thr22Asn
- ExAC rs750005260
- gnomAD rs750005260
- Missense
- Variant Prioritization Score for Impact Estimate 0.348
- REVEL 0.17
- CADD 22.10
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available