T20S (p.Thr20Ser) variant of HLA-A (P04439)
T20S (p.Thr20Ser) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
T20S (p.Thr20Ser) variant details
- p.Thr20Ser
- gnomAD 6-29942611-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- REVEL 0.14
- CADD 23.10
- PolyPhen-2 0.99
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available