P6H (p.Pro6His) variant of HLA-A (P04439)
P6H (p.Pro6His) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
P6H (p.Pro6His) variant details
- p.Pro6His
- gnomAD rs1292284887
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.14
- CADD 18.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.5e-05)
- Structural context available