M4R (p.Met4Arg) variant of HLA-A (P04439)
M4R (p.Met4Arg) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
M4R (p.Met4Arg) variant details
- p.Met4Arg
- 1000Genomes rs555527051
- gnomAD rs555527051
- Missense
- Variant Prioritization Score for Impact Estimate 0.331
- REVEL 0.23
- CADD 17.50
- PolyPhen-2 0.40
- SIFT 0.03
- Most common in the 1KG:YRI population (allele frequency 0.0051)
- Structural context available