L9R (p.Leu9Arg) variant of HLA-A (P04439)
L9R (p.Leu9Arg) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
L9R (p.Leu9Arg) variant details
- p.Leu9Arg
- cosmic curated COSV65138
- Missense
- Variant Prioritization Score for Impact Estimate 0.362
- REVEL 0.25
- CADD 22.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 3.5e-05)
- Structural context available