L9I (p.Leu9Ile) variant of HLA-A (P04439)
L9I (p.Leu9Ile) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
L9I (p.Leu9Ile) variant details
- p.Leu9Ile
- gnomAD rs1450362906
- Missense
- Variant Prioritization Score for Impact Estimate 0.289
- REVEL 0.09
- CADD 19.10
- PolyPhen-2 0.99
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 3.9e-05)
- Structural context available