L9F (p.Leu9Phe) variant of HLA-A (P04439)
L9F (p.Leu9Phe) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
L9F (p.Leu9Phe) variant details
- p.Leu9Phe
- gnomAD rs1450362906
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.10
- CADD 16.20
- PolyPhen-2 1.00
- SIFT 0.15
- Most common in the African/African-American population (allele frequency 3.1e-05)
- Structural context available