L17W (p.Leu17Trp) variant of HLA-A (P04439)
L17W (p.Leu17Trp) in HLA-A (P04439) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
L17W (p.Leu17Trp) variant details
- p.Leu17Trp
- gnomAD 6-29942599-GC-G
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.224
- CADD 20.20
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available