L17R (p.Leu17Arg) variant of HLA-A (P04439)
L17R (p.Leu17Arg) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
L17R (p.Leu17Arg) variant details
- p.Leu17Arg
- gnomAD 6-29942603-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.247
- REVEL 0.24
- CADD 23.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4e-05)
- Structural context available
- Literature evidence available