L17M (p.Leu17Met) variant of HLA-A (P04439)
L17M (p.Leu17Met) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
L17M (p.Leu17Met) variant details
- p.Leu17Met
- ExAC rs751524208
- gnomAD rs751524208
- Missense
- Variant Prioritization Score for Impact Estimate 0.343
- REVEL 0.16
- CADD 22.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4e-05)
- Structural context available