L12Y (p.Leu12Tyr) variant of HLA-A (P04439)
L12Y (p.Leu12Tyr) in HLA-A (P04439) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
L12Y (p.Leu12Tyr) variant details
- p.Leu12Tyr
- gnomAD 6-29942585-TG-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.512
- CADD 23.10
- Population evidence available
- Structural context available
- Literature evidence available