L11M (p.Leu11Met) variant of HLA-A (P04439)
L11M (p.Leu11Met) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
L11M (p.Leu11Met) variant details
- p.Leu11Met
- cosmic curated COSV10611
- ESP rs142768093
- ExAC rs142768093
- gnomAD rs142768093
- Missense
- Variant Prioritization Score for Impact Estimate 0.338
- REVEL 0.15
- CADD 23.00
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 0.00014)
- Structural context available