L10F (p.Leu10Phe) variant of HLA-A (P04439)
L10F (p.Leu10Phe) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
L10F (p.Leu10Phe) variant details
- p.Leu10Phe
- 1000Genomes rs1143146
- ESP rs1143146
- ExAC rs1143146
- gnomAD rs1143146
- Missense
- Variant Prioritization Score for Impact Estimate 0.0699
- REVEL 0.02
- CADD 10.70
- PolyPhen-2 0.17
- SIFT 0.06
- Most common in the South Asian population (allele frequency 1.7e-05)
- Structural context available