G25V (p.Gly25Val) variant of HLA-A (P04439)
G25V (p.Gly25Val) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
G25V (p.Gly25Val) variant details
- p.Gly25Val
- gnomAD 6-29942757-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.39
- REVEL 0.20
- CADD 31.00
- PolyPhen-2 0.98
- SIFT 0.01
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.6e-05)
- Structural context available
- Literature evidence available