G25R (p.Gly25Arg) variant of HLA-A (P04439)
G25R (p.Gly25Arg) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
G25R (p.Gly25Arg) variant details
- p.Gly25Arg
- ExAC rs200993279
- gnomAD rs200993279
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- REVEL 0.13
- CADD 30.00
- PolyPhen-2 0.31
- SIFT 0.01
- Most common in the East Asian population (allele frequency 3.6e-05)
- Structural context available