G25C (p.Gly25Cys) variant of HLA-A (P04439)
G25C (p.Gly25Cys) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
G25C (p.Gly25Cys) variant details
- p.Gly25Cys
- gnomAD 6-29942626-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.416
- REVEL 0.23
- CADD 33.00
- PolyPhen-2 0.99
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.3e-06)
- Structural context available
- Literature evidence available