A2T (p.Ala2Thr) variant of HLA-A (P04439)
A2T (p.Ala2Thr) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
A2T (p.Ala2Thr) variant details
- p.Ala2Thr
- Ensembl rs1770933332
- Missense
- Variant Prioritization Score for Impact Estimate 0.29
- REVEL 0.14
- CADD 12.40
- PolyPhen-2 0.22
- SIFT 0.51
- Most common in the East Asian population (allele frequency 3.3e-05)
- Structural context available