A2S (p.Ala2Ser) variant of HLA-A (P04439)
A2S (p.Ala2Ser) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
A2S (p.Ala2Ser) variant details
- p.Ala2Ser
- gnomAD 6-29942557-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- REVEL 0.17
- CADD 11.40
- PolyPhen-2 0.22
- SIFT 0.62
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.7e-05)
- Structural context available
- Literature evidence available