A18S (p.Ala18Ser) variant of HLA-A (P04439)
A18S (p.Ala18Ser) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
A18S (p.Ala18Ser) variant details
- p.Ala18Ser
- gnomAD rs1454564491
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.13
- CADD 20.90
- PolyPhen-2 0.45
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 2.5e-06)
- Structural context available