A18G (p.Ala18Gly) variant of HLA-A (P04439)
A18G (p.Ala18Gly) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
A18G (p.Ala18Gly) variant details
- p.Ala18Gly
- TOPMed rs1279237267
- gnomAD rs1279237267
- Missense
- Variant Prioritization Score for Impact Estimate 0.305
- REVEL 0.14
- CADD 16.80
- PolyPhen-2 0.53
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 2.5e-06)
- Structural context available