A18D (p.Ala18Asp) variant of HLA-A (P04439)
A18D (p.Ala18Asp) in HLA-A (P04439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
A18D (p.Ala18Asp) variant details
- p.Ala18Asp
- gnomAD 6-29942606-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.372
- REVEL 0.25
- CADD 17.50
- PolyPhen-2 0.80
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available