K21K (p.Lys21Lys) variant of HIF1A (Hypoxia-inducible factor 1-alpha)
K21K (p.Lys21Lys) in HIF1A (Hypoxia-inducible factor 1-alpha) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
K21K (p.Lys21Lys) variant details
- p.Lys21Lys
- gnomAD 14-61697919-A-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.231
- CADD 10.00
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available
- Literature evidence available