A26G (p.Ala26Gly) variant of HIF1A (Hypoxia-inducible factor 1-alpha)
A26G (p.Ala26Gly) in HIF1A (Hypoxia-inducible factor 1-alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data, published literature, and structural context.
A26G (p.Ala26Gly) variant details
- p.Ala26Gly
- gnomAD 14-61720423-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.518
- REVEL 0.39
- MetaLR 0.34
- MetaSVM -0.09
- CADD 25.20
- PolyPhen-2 0.51
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available