R66R (p.Arg66Arg) variant of HFE (Q30201)
R66R (p.Arg66Arg) in HFE (Q30201) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
R66R (p.Arg66Arg) variant details
- p.Arg66Arg
- gnomAD 6-26090962-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.244
- CADD 6.64
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available
- Literature evidence available