M35V (p.Met35Val) variant of HFE (Q30201)
M35V (p.Met35Val) in HFE (Q30201) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
M35V (p.Met35Val) variant details
- p.Met35Val
- gnomAD rs1762646075
- Missense
- Variant Prioritization Score for Impact Estimate 0.146
- REVEL 0.03
- CADD 16.40
- PolyPhen-2 0.02
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available