T99P (p.Thr99Pro) variant of HCN1 (O60741)
T99P (p.Thr99Pro) in HCN1 (O60741) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
T99P (p.Thr99Pro) variant details
- p.Thr99Pro
- ExAC rs779325604
- Missense
- Variant Prioritization Score for Impact Estimate 0.361
- REVEL 0.28
- CADD 22.90
- PolyPhen-2 0.42
- SIFT 0.01
- Population evidence available
- Structural context available