S10L (p.Ser10Leu) variant of HCN1 (O60741)
S10L (p.Ser10Leu) in HCN1 (O60741) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
S10L (p.Ser10Leu) variant details
- p.Ser10Leu
- TOPMed rs1453769463
- Missense
- Variant Prioritization Score for Impact Estimate 0.446
- REVEL 0.33
- CADD 19.50
- PolyPhen-2 0.00
- SIFT 0.71
- Population evidence available
- Structural context available