N8S (p.Asn8Ser) variant of HCN1 (O60741)
N8S (p.Asn8Ser) in HCN1 (O60741) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
N8S (p.Asn8Ser) variant details
- p.Asn8Ser
- gnomAD rs1445930484
- Missense
- Variant Prioritization Score for Impact Estimate 0.303
- REVEL 0.22
- CADD 20.10
- PolyPhen-2 0.00
- SIFT 0.23
- Most common in the East Asian population (allele frequency 4.7e-05)
- Structural context available