G74V (p.Gly74Val) variant of HCN1 (O60741)
G74V (p.Gly74Val) in HCN1 (O60741) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
G74V (p.Gly74Val) variant details
- p.Gly74Val
- TOPMed rs1282259414
- gnomAD rs1282259414
- Missense
- Variant Prioritization Score for Impact Estimate 0.388
- REVEL 0.44
- CADD 15.30
- PolyPhen-2 0.09
- SIFT 0.17
- Population evidence available
- Structural context available