G74D (p.Gly74Asp) variant of HCN1 (O60741)
G74D (p.Gly74Asp) in HCN1 (O60741) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
G74D (p.Gly74Asp) variant details
- p.Gly74Asp
- TOPMed rs1282259414
- gnomAD rs1282259414
- Missense
- Variant Prioritization Score for Impact Estimate 0.38
- REVEL 0.42
- CADD 14.70
- PolyPhen-2 0.17
- SIFT 0.41
- Population evidence available
- Structural context available