G69S (p.Gly69Ser) variant of HCN1 (O60741)
G69S (p.Gly69Ser) in HCN1 (O60741) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
G69S (p.Gly69Ser) variant details
- p.Gly69Ser
- gnomAD rs1201375181
- Missense
- Variant Prioritization Score for Impact Estimate 0.325
- REVEL 0.37
- CADD 14.10
- PolyPhen-2 0.00
- SIFT 0.37
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available