G63S (p.Gly63Ser) variant of HCN1 (O60741)
G63S (p.Gly63Ser) in HCN1 (O60741) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
G63S (p.Gly63Ser) variant details
- p.Gly63Ser
- gnomAD rs1406370096
- Missense
- Variant Prioritization Score for Impact Estimate 0.366
- REVEL 0.22
- CADD 18.90
- PolyPhen-2 0.01
- SIFT 0.50
- Population evidence available
- Structural context available