G4S (p.Gly4Ser) variant of HCN1 (O60741)
G4S (p.Gly4Ser) in HCN1 (O60741) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
G4S (p.Gly4Ser) variant details
- p.Gly4Ser
- Ensembl rs1740007380
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- REVEL 0.30
- CADD 15.90
- PolyPhen-2 0.00
- SIFT 0.48
- Most common in the REMAINING population (allele frequency 2.2e-05)
- Structural context available