A84S (p.Ala84Ser) variant of HCN1 (O60741)
A84S (p.Ala84Ser) in HCN1 (O60741) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
A84S (p.Ala84Ser) variant details
- p.Ala84Ser
- gnomAD rs1256720723
- Missense
- Variant Prioritization Score for Impact Estimate 0.327
- REVEL 0.33
- CADD 17.80
- PolyPhen-2 0.32
- SIFT 0.40
- Most common in the East Asian population (allele frequency 2.6e-05)
- Structural context available