A27G (p.Ala27Gly) variant of HCN1 (O60741)
A27G (p.Ala27Gly) in HCN1 (O60741) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
A27G (p.Ala27Gly) variant details
- p.Ala27Gly
- TOPMed rs1461851528
- gnomAD rs1461851528
- Missense
- Variant Prioritization Score for Impact Estimate 0.357
- REVEL 0.26
- CADD 16.20
- PolyPhen-2 0.00
- SIFT 0.27
- Most common in the Non-Finnish European population (allele frequency 2.1e-06)
- Structural context available